Time Dependency of Factors Affecting Renal Allograft Survival

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patient survival in renal allograft failure: a time-dependent analysis

patients and methods this retrospective cohort study included 405 renal transplant patients from kerman university of medical sciences hospital, kerman, iran from 2004 to 2010. kaplan-meier method was used to estimate survival rates of patients, and time-dependent cox regression was used to examine the effect of allograft failure on patient survival. results during 4.06 years (median) of follow...

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Patient Survival in Renal Allograft Failure: A Time-dependent Analysis

BACKGROUND To improve patient survival after a renal transplant, it is important to detect which variables affect it. OBJECTIVES This study aimed to assess the effect of renal allograft failure on patient survival. PATIENTS AND METHODS This retrospective cohort study included 405 renal transplant patients from Kerman University of Medical Sciences hospital, Kerman, Iran from 2004 to 2010. K...

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Association of CCR5-59029 A/G and CCR2-V64I Variants with Renal Allograft Survival

Background: Despite advances in the medical care of renal transplant recipients which have led to an improvement in allograft survival, renal allograft rejection is still a major ob-stacle to successful organ transplantation. Understanding the mechanisms contributing to allograft rejection will be of great importance for the development of efficient antirejection strategies. Objective: The aim ...

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Deficiency of C5aR prolongs renal allograft survival.

Interaction between C5a, a product of complement activation, and its receptor (C5aR) upregulates antigen-specific T cell responses by modulating the activation of antigen-presenting cells and T cells. Whether this C5a-C5aR interaction contributes to the immune responses that promote renal allograft rejection is unknown. Here, we found that deficiency of C5aR in both graft and recipient reduced ...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 2000

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.v113565